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Target
Galectin-8
Ligand
BDBM50326602
Substrate
n/a
Meas. Tech.
ChEMBL_661837 (CHEMBL1252153)
Kd
>5000000±n/a nM
Citation
 Salameh, BA; Cumpstey, I; Sundin, A; Leffler, H; Nilsson, UJ 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorg Med Chem 18:5367-78 (2010) [PubMed]  Article 
Target
Name:
Galectin-8
Synonyms:
Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1
Type:
PROTEIN
Mol. Mass.:
35814.23
Organism:
Human
Description:
ChEMBL_1454625
Residue:
317
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
  
Inhibitor
Name:
BDBM50326602
Synonyms:
CHEMBL1254599 | Methyl-3-deoxy-3-(4-phenyl-1H-[1,2,3]-triazol-1-yl)-1-thio-beta-D-galactopyranoside
Type:
Small organic molecule
Emp. Form.:
C15H19N3O4S
Mol. Mass.:
337.394
SMILES:
CS[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)-c1ccccc1 |r|
Structure:
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