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Target
Beta-1 adrenergic receptor
Ligand
BDBM50404501
Substrate
n/a
Meas. Tech.
ChEMBL_76500 (CHEMBL687609)
Kd
195±n/a nM
Citation
 Leclerc, G; Bieth, N; Schwartz, J Synthesis and beta-adrenergic blocking activity of new aliphatic oxime ethers. J Med Chem 23:620-4 (1980) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50404501
Synonyms:
CHEMBL1161384
Type:
Small organic molecule
Emp. Form.:
C11H24N2O2
Mol. Mass.:
216.3205
SMILES:
CC\C(C)=N/OCC(O)CNC(C)(C)C
Structure:
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