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Target
Motilin receptor
Ligand
BDBM50412902
Substrate
n/a
Meas. Tech.
ChEMBL_519557 (CHEMBL942680)
EC50
398.11±n/a nM
Citation
 Heightman, TD; Conway, E; Corbett, DF; Macdonald, GJ; Stemp, G; Westaway, SM; Celestini, P; Gagliardi, S; Riccaboni, M; Ronzoni, S; Vaidya, K; Butler, S; McKay, F; Muir, A; Powney, B; Winborn, K; Wise, A; Jarvie, EM; Sanger, GJ Identification of small molecule agonists of the motilin receptor. Bioorg Med Chem Lett 18:6423-8 (2008) [PubMed]  Article 
Target
Name:
Motilin receptor
Synonyms:
G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN
Type:
PROTEIN
Mol. Mass.:
45365.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_122664
Residue:
412
Sequence:
MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
  
Inhibitor
Name:
BDBM50412902
Synonyms:
CHEMBL515275
Type:
Small organic molecule
Emp. Form.:
C35H45N3O2
Mol. Mass.:
539.7507
SMILES:
COc1cccc(CCN(Cc2ccccc2-c2ccc(CC3CCNCC3)cc2)C(=O)NC2CCCCC2)c1
Structure:
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