Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM35873
Substrate
n/a
Meas. Tech.
ChEMBL_500314 (CHEMBL973406)
IC50
8.13±n/a nM
Citation
 Kang, NS; Lee, GN; Yoo, SE Predictive models of Cannabinoid-1 receptor antagonists derived from diverse classes. Bioorg Med Chem Lett 19:2990-6 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM35873
Synonyms:
5,6-bis(4-chlorophenyl)-N-(piperidin-1-yl)pyrazine-2-carboxamide | 5,6-bis-(4-chloro-phenyl)-pyrazine-2-carboxylic acidpiperidin-1-ylamide | 5,6-diaryl-pyrazine-2-amide derivative, 5e | CHEMBL390146
Type:
Small organic molecule
Emp. Form.:
C22H20Cl2N4O
Mol. Mass.:
427.326
SMILES:
Clc1ccc(cc1)-c1ncc(nc1-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Structure:
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