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Target
D(2) dopamine receptor
Ligand
BDBM71863
Substrate
n/a
Meas. Tech.
ChEMBL_605062 (CHEMBL1071924)
Ki
>10000±n/a nM
Citation
 D'Alessandro, PL; Corti, C; Roth, A; Ugolini, A; Sava, A; Montanari, D; Bianchi, F; Garland, SL; Powney, B; Koppe, EL; Rocheville, M; Osborne, G; Perez, P; de la Fuente, J; De Los Frailes, M; Smith, PW; Branch, C; Nash, D; Watson, SP The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2. Bioorg Med Chem Lett 20:759-62 (2010) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM71863
Synonyms:
2-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1-methylbenzimidazole | 2-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-1-methyl-benzimidazole | 2-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-1-methylbenzimidazole | 2-[[4-(4-chlorophenyl)piperazino]methyl]-1-methyl-benzimidazole | MLS000112495 | SMR000108409 | cid_798232
Type:
Small organic molecule
Emp. Form.:
C19H21ClN4
Mol. Mass.:
340.85
SMILES:
Cn1c(CN2CCN(CC2)c2ccc(Cl)cc2)nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: