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Target
Motilin receptor
Ligand
BDBM50421352
Substrate
n/a
Meas. Tech.
ChEMBL_122668 (CHEMBL879670)
IC50
155±n/a nM
Citation
 Koga, H; Sato, T; Tsuzuki, K; Onoda, H; Kuboniwa, H; Takanashi, H Potent, acid-stable and orally active macrolide-type motilin receptor agonists, GM-611 and the derivatives Bioorg Med Chem Lett 4:1347-1352 (1994)    Article 
Target
Name:
Motilin receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
43771.25
Organism:
Oryctolagus cuniculus
Description:
n/a
Residue:
400
Sequence:
MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTVLLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEGCTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVEQDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVTTAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWLPFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRESRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
  
Inhibitor
Name:
BDBM50421352
Synonyms:
CHEMBL281952
Type:
Small organic molecule
Emp. Form.:
C37H65NO12
Mol. Mass.:
715.9115
SMILES:
CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)C3(O2)O[C@]1(C)[C@H](O)[C@H]3C
Structure:
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