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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM50013804
Substrate
n/a
Meas. Tech.
ChEMBL_943579 (CHEMBL2343392)
Ki
3000±n/a nM
Citation
 Tanaka, M; Li, X; Hikawa, H; Suzuki, T; Tsutsumi, K; Sato, M; Takikawa, O; Suzuki, H; Yokoyama, Y Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors. Bioorg Med Chem 21:1159-65 (2013) [PubMed]  Article 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Human
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM50013804
Synonyms:
10,13-Dimethyl-hexadecahydro-cyclopenta[a]phenanthrene-3,17-diol | 3-Butyl-9H-beta-carboline | CHEMBL69488
Type:
Small organic molecule
Emp. Form.:
C15H16N2
Mol. Mass.:
224.3009
SMILES:
CCCCc1cc2c(c[nH]1)nc1ccccc21
Structure:
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