Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50432196
Substrate
n/a
Meas. Tech.
ChEMBL_950672 (CHEMBL2352675)
Ki
333±n/a nM
Citation
 Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett 23:2019-21 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50432196
Synonyms:
CHEMBL2346668
Type:
Small organic molecule
Emp. Form.:
C23H21BrN2O
Mol. Mass.:
421.33
SMILES:
Brc1ccccc1Cn1cc(C=C2N3CCC(CC3)C2=O)c2ccccc12 |w:11.11,(29.07,-25.6,;27.53,-25.55,;26.72,-26.85,;25.18,-26.81,;24.46,-25.44,;25.27,-24.14,;26.81,-24.2,;27.63,-22.89,;26.9,-21.53,;27.81,-20.29,;26.9,-19.04,;27.38,-17.57,;28.88,-17.25,;29.91,-18.41,;31.41,-18.09,;31.89,-16.63,;30.87,-15.48,;30.81,-16.72,;29.99,-16.78,;29.35,-15.8,;28.33,-14.65,;25.44,-19.52,;24.1,-18.75,;22.77,-19.52,;22.77,-21.07,;24.1,-21.84,;25.44,-21.06,)|
Structure:
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