Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50435802
Substrate
n/a
Meas. Tech.
ChEMBL_963568 (CHEMBL2394755)
Ki
90±n/a nM
Citation
 Ruel, R; L'Heureux, A; Thibeault, C; Daris, JP; Martel, A; Price, LA; Wu, Q; Hua, J; Wexler, RR; Rehfuss, R; Lam, PY New azole antagonists with high affinity for the P2Y(1) receptor. Bioorg Med Chem Lett 23:3519-22 (2013) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50435802
Synonyms:
CHEMBL2393195
Type:
Small organic molecule
Emp. Form.:
C20H22N4O3S
Mol. Mass.:
398.479
SMILES:
CCOC(=O)c1nnc(Nc2cccnc2Oc2ccccc2C(C)(C)C)s1
Structure:
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