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Target
Macrophage inflammatory protein-1 alpha receptor
Ligand
BDBM50444995
Substrate
n/a
Meas. Tech.
ChEMBL_1281523 (CHEMBL3102089)
IC50
>6000±n/a nM
Citation
Hossain, N; Mensonides-Harsema, M; Cooper, ME; Eriksson, T; Ivanova, S; Bergström, L Structure activity relationships of fused bicyclic and urea derivatives of spirocyclic compounds as potent CCR1 antagonists. Bioorg Med Chem Lett 24:108-12 (2013) [PubMed] Article
More Info.:
Target
Name:
Macrophage inflammatory protein-1 alpha receptor
Synonyms:
C-C chemokine receptor type 1
Type:
PROTEIN
Mol. Mass.:
40846.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1281523
Residue:
355
Sequence:
MEISNITETYPTTTEYDYGDSTPCQKTDVRAFGAGLLPPLYSFVFIIGVVGNILVILVLMQHRRLQSMTSIYLFNLAVSDLVFLFTLPFWIDYKLKDNWVFGDAMCKLLSGFYYLGLYSEIFFIILLTIDRYLAIVHAVFSLRARTVTFGIITSIIIWALAILASIPALCFFKAQWEFTHHTCSPHFPDESLKTWKRFQALKLNLLGLILPLLVMIICYAGIIRILLRRPNEKKAKAVRLIFAITLLFFLLWTPYNLTVFVSAFQDVLFTNQCEQSKQLDLAIQVTEVIAYTHCCVNPIIYVFVGERFRKYLRQLFQRHVAIPLAKWLPFFSVDQLERTSSLTPSTGEHELSGGF