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Target
Arylamine N-acetyltransferase 2
Ligand
BDBM50014986
Substrate
n/a
Meas. Tech.
ChEMBL_1347887 (CHEMBL3267123)
IC50
270±n/a nM
Citation
 Egleton, JE; Thinnes, CC; Seden, PT; Laurieri, N; Lee, SP; Hadavizadeh, KS; Measures, AR; Jones, AM; Thompson, S; Varney, A; Wynne, GM; Ryan, A; Sim, E; Russell, AJ Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1. Bioorg Med Chem 22:3030-54 (2014) [PubMed]  Article 
Target
Name:
Arylamine N-acetyltransferase 2
Synonyms:
ARY2_MOUSE | Aac2 | Nat2
Type:
PROTEIN
Mol. Mass.:
33697.98
Organism:
Mus musculus
Description:
ChEMBL_1347887
Residue:
290
Sequence:
MDIEAYFERIGYQSTRSKLDLKTLTEILQHQIRAIPFENLNIHCGESMELSLEAIFDQIVRKKRGGWCLQVNHLLYWALTKLGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFINSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGSTLTYRRFSYKDNVDLVEFKSLTEEEIEDVLRTIFGVSLERKLVPKHGDRFFTI
  
Inhibitor
Name:
BDBM50014986
Synonyms:
CHEMBL3262086
Type:
Small organic molecule
Emp. Form.:
C22H17N3O4S
Mol. Mass.:
419.453
SMILES:
Nc1cccc2C(=O)C(Nc3ccccc3)=C(NS(=O)(=O)c3ccccc3)C(=O)c12 |t:16|
Structure:
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