Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50021063
Substrate
n/a
Meas. Tech.
ChEMBL_1365880 (CHEMBL3296538)
Ki
5930±n/a nM
Citation
 Li, D; Wu, Z; Yu, Y; Ball, RG; Guo, L; Sherer, E; He, S; Hong, Q; Lai, Z; Qi, H; Truong, Q; Yang, DX; Chicchi, GG; Tsao, KL; Trusca, D; Trujillo, M; Pachanski, M; Eiermann, GJ; Howard, AD; Zhou, YP; Zhang, BB; Nargund, RP; Hagmann, WK Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists. ACS Med Chem Lett 5:690-5 (2014) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Human
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50021063
Synonyms:
CHEMBL3287613
Type:
Small organic molecule
Emp. Form.:
C22H24FN3O
Mol. Mass.:
365.4439
SMILES:
Fc1ccc(cc1)C(=O)N[C@@H]1CCCC[C@@H]1NCc1c[nH]c2ccccc12 |r|
Structure:
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