Reaction Details Report a problem with these data
Target
Galectin-8
Ligand
BDBM21540
Substrate
n/a
Meas. Tech.
ChEMBL_1454625 (CHEMBL3361814)
Kd
>2000000±n/a nM
Citation
 Rajput, VK; Leffler, H; Nilsson, UJ; Mukhopadhyay, B Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists. Bioorg Med Chem Lett 24:3516-20 (2014) [PubMed]  Article 
Target
Name:
Galectin-8
Synonyms:
Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1
Type:
PROTEIN
Mol. Mass.:
35814.23
Organism:
Human
Description:
ChEMBL_1454625
Residue:
317
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
  
Inhibitor
Name:
BDBM21540
Synonyms:
Galactose-Derived Compound 18 | N-[(2R,3R,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(methylsulfanyl)oxan-4-yl]-4-methylbenzamide
Type:
Small organic molecule
Emp. Form.:
C15H21NO5S
Mol. Mass.:
327.396
SMILES:
CS[C@@H]1O[C@H](CO)[C@H](O)[C@H](NC(=O)c2ccc(C)cc2)[C@H]1O
Structure:
Search PDB for entries with ligand similarity: