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Target
Krueppel-like factor 10
Ligand
BDBM50071813
Substrate
n/a
Meas. Tech.
ChEMBL_1467056 (CHEMBL3411253)
IC50
43000±n/a nM
Citation
 Khedkar, SA; Sun, X; Rigby, AC; Feinberg, MW Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation. J Med Chem 58:1466-78 (2015) [PubMed]  Article 
Target
Name:
Krueppel-like factor 10
Synonyms:
EGR-alpha | KLF10 | KLF10_HUMAN | Krueppel-like factor 10 | TGFB-inducible early growth response protein 1 | TIEG | TIEG | TIEG-1 | TIEG1 | Transforming growth factor-beta-inducible early growth response protein 1
Type:
PROTEIN
Mol. Mass.:
52579.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109571
Residue:
480
Sequence:
MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
  
Inhibitor
Name:
BDBM50071813
Synonyms:
CHEMBL2179992
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4S2
Mol. Mass.:
362.423
SMILES:
Cc1sc2nc(SCC(=O)c3ccc(O)c(O)c3)[nH]c(=O)c2c1C
Structure:
Search PDB for entries with ligand similarity: