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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50092134
Substrate
n/a
Meas. Tech.
ChEMBL_1498846 (CHEMBL3583820)
EC50
37±n/a nM
Citation
 Singh, A; Tala, SR; Flores, V; Freeman, K; Haskell-Luevano, C Synthesis and Pharmacology ofa/ß(3)-Peptides Based on the Melanocortin Agonist Ac-His-dPhe-Arg-Trp-NH2 Sequence. ACS Med Chem Lett 6:568-72 (2015) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r
Type:
PROTEIN
Mol. Mass.:
35238.60
Organism:
Mouse
Description:
ChEMBL_1498846
Residue:
315
Sequence:
MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIAITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDVLICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITYYKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAATLTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRSQELRMTLKEVLLCSW
  
Inhibitor
Name:
BDBM50092134
Synonyms:
CHEMBL3582445
Type:
Small organic molecule
Emp. Form.:
C35H45N11O5
Mol. Mass.:
699.8025
SMILES:
CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r|
Structure:
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