Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50144614
Substrate
n/a
Meas. Tech.
ChEMBL_1551637 (CHEMBL3760883)
Ki
1725±n/a nM
Citation
 Fulp, A; Zhang, Y; Bortoff, K; Seltzman, H; Snyder, R; Wiethe, R; Amato, G; Maitra, R Pyrazole antagonists of the CB1 receptor with reduced brain penetration. Bioorg Med Chem 24:1063-70 (2016) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50144614
Synonyms:
CHEMBL3758884
Type:
Small organic molecule
Emp. Form.:
C29H25Cl3N4O2
Mol. Mass.:
567.893
SMILES:
Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)c1ccccc1
Structure:
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