Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50230370
Substrate
n/a
Meas. Tech.
ChEMBL_1644841 (CHEMBL3993770)
Ki
158±n/a nM
Citation
 Iyer, MR; Cinar, R; Katz, A; Gao, M; Erdelyi, K; Jourdan, T; Coffey, NJ; Pacher, P; Kunos, G Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB J Med Chem 60:1126-1141 (2017) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50230370
Synonyms:
CHEMBL4097409
Type:
Small organic molecule
Emp. Form.:
C29H22Cl3N5O2S
Mol. Mass.:
610.941
SMILES:
N\C(=N\C(=N/S(=O)(=O)c1ccc(Cl)cc1)\N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1)c1ccc(Cl)cc1 |c:19|
Structure:
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