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Target
G-protein coupled receptor 39
Ligand
BDBM50232402
Substrate
n/a
Meas. Tech.
ChEMBL_1646463 (CHEMBL3995519)
EC50
1.000000±n/a nM
Citation
 Frimurer, TM; Mende, F; Graae, AS; Engelstoft, MS; Egerod, KL; Nygaard, R; Gerlach, LO; Hansen, JB; Schwartz, TW; Holst, B Model-Based Discovery of Synthetic Agonists for the Zn J Med Chem 60:886-898 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 39
Synonyms:
GPR39 | GPR39_HUMAN
Type:
PROTEIN
Mol. Mass.:
51351.94
Organism:
Human
Description:
ChEMBL_107977
Residue:
453
Sequence:
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
  
Inhibitor
Name:
BDBM50232402
Synonyms:
CHEMBL4072160
Type:
Small organic molecule
Emp. Form.:
C19H16FN7O2
Mol. Mass.:
393.3744
SMILES:
Cc1nn(c2NC(=O)CC(OCc3ccc(F)cc3)c12)-c1ncnc2nc[nH]c12
Structure:
Search PDB for entries with ligand similarity: