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Target
G-protein coupled receptor 39
Ligand
BDBM50232393
Substrate
n/a
Meas. Tech.
ChEMBL_1646463 (CHEMBL3995519)
EC50
5.0±n/a nM
Citation
 Frimurer, TM; Mende, F; Graae, AS; Engelstoft, MS; Egerod, KL; Nygaard, R; Gerlach, LO; Hansen, JB; Schwartz, TW; Holst, B Model-Based Discovery of Synthetic Agonists for the Zn J Med Chem 60:886-898 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 39
Synonyms:
GPR39 | GPR39_HUMAN
Type:
PROTEIN
Mol. Mass.:
51351.94
Organism:
Human
Description:
ChEMBL_107977
Residue:
453
Sequence:
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
  
Inhibitor
Name:
BDBM50232393
Synonyms:
CHEMBL4081885
Type:
Small organic molecule
Emp. Form.:
C20H18N8O2
Mol. Mass.:
402.4093
SMILES:
Cc1nn(c2NC(=O)CC(C(=O)NCc3ccccc3)c12)-c1ncnc2nc[nH]c12
Structure:
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