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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90229
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90229
Synonyms:
1-(2-methyl-3-phenyl-2-propen-1-yl)-4-(1-piperidinylcarbonyl)piperidine oxalate | MLS000680909 | SMR000269572 | [1-[(E)-2-methyl-3-phenyl-allyl]-4-piperidyl]-piperidino-methanone;oxalic acid | [1-[(E)-2-methyl-3-phenylprop-2-enyl]-4-piperidinyl]-(1-piperidinyl)methanone;oxalic acid | [1-[(E)-2-methyl-3-phenylprop-2-enyl]piperidin-4-yl]-piperidin-1-ylmethanone;oxalic acid | cid_5731005 | ethanedioic acid;[1-[(E)-2-methyl-3-phenyl-prop-2-enyl]piperidin-4-yl]-piperidin-1-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C21H30N2O
Mol. Mass.:
326.4757
SMILES:
C\C(CN1CCC(CC1)C(=O)N1CCCCC1)=C/c1ccccc1
Structure:
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