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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90877
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90877
Synonyms:
3-[(3-fluorobenzoyl)amino]-5-phenyl-2-thenoic acid | 3-[(3-fluorobenzoyl)amino]-5-phenylthiophene-2-carboxylic acid | 3-[(3-fluorophenyl)carbonylamino]-5-phenyl-thiophene-2-carboxylic acid | 3-[[(3-fluorophenyl)-oxomethyl]amino]-5-phenyl-2-thiophenecarboxylic acid | MLS001199048 | SMR000563201 | cid_16012569
Type:
Small organic molecule
Emp. Form.:
C18H12FNO3S
Mol. Mass.:
341.356
SMILES:
OC(=O)c1sc(cc1NC(=O)c1cccc(F)c1)-c1ccccc1
Structure:
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