Reaction Details Report a problem with these data
Target
Cathepsin L
Ligand
BDBM93172
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
5.5±0
Ki
120±0.0 nM
Citation
Yamashita, DS; Dong, X; Oh, HJ; Brook, CS; Tomaszek, TA; Szewczuk, L; Tew, DG; Veber, DF Solid-phase synthesis of a combinatorial array of 1,3-bis(acylamino)-2-butanones, inhibitors of the cysteine proteases cathepsins K and L. J Comb Chem 1:207-15 (1999) [PubMed] Article
More Info.:
Target
Name:
Cathepsin L
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
19098.77
Organism:
Human
Description:
Q6LAF7
Residue:
175
Sequence:
VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESSESDNNKYWLVKN