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Target
Protein skinhead-1
Ligand
BDBM93758
Substrate
n/a
IC50
13200±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93758
Synonyms:
MLS000534624 | N-[4-(5-chloranylthiophen-2-yl)-1,3-thiazol-2-yl]benzamide | N-[4-(5-chloro-2-thienyl)-1,3-thiazol-2-yl]benzamide | N-[4-(5-chloro-2-thienyl)thiazol-2-yl]benzamide | N-[4-(5-chloro-2-thiophenyl)-2-thiazolyl]benzamide | N-[4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-yl]benzamide | SMR000142061 | cid_801259
Type:
Small organic molecule
Emp. Form.:
C14H9ClN2OS2
Mol. Mass.:
320.817
SMILES:
Clc1ccc(s1)-c1csc(NC(=O)c2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: