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Target
Protein skinhead-1
Ligand
BDBM93776
Substrate
n/a
IC50
11800±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93776
Synonyms:
MLS000580501 | N-[[3-chloranyl-4-[(4-fluorophenyl)methoxy]-5-methoxy-phenyl]methyl]cyclopentanamine;hydrochloride | N-[[3-chloro-4-[(4-fluorophenyl)methoxy]-5-methoxyphenyl]methyl]cyclopentanamine;hydrochloride | N-{3-chloro-4-[(4-fluorobenzyl)oxy]-5-methoxybenzyl}cyclopentanamine hydrochloride | SMR000199388 | [3-chloro-4-(4-fluorobenzyl)oxy-5-methoxy-benzyl]-cyclopentyl-amine;hydrochloride | cid_2950356
Type:
Small organic molecule
Emp. Form.:
C20H23ClFNO2
Mol. Mass.:
363.854
SMILES:
COc1cc(CNC2CCCC2)cc(Cl)c1OCc1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: