Reaction Details Report a problem with these data
Target
Protein Wnt-3a
Ligand
BDBM54412
Substrate
n/a
IC50
491±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM54412
Synonyms:
1-[1-(2-Fluoro-benzyl)-1H-indol-3-yl]-ethanone | 1-[1-(2-fluorobenzyl)indol-3-yl]ethanone | 1-[1-[(2-fluorophenyl)methyl]-3-indolyl]ethanone | 1-[1-[(2-fluorophenyl)methyl]indol-3-yl]ethanone | MLS001205533 | SMR000524010 | cid_951679
Type:
Small organic molecule
Emp. Form.:
C17H14FNO
Mol. Mass.:
267.2976
SMILES:
CC(=O)c1cn(Cc2ccccc2F)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: