Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93722
Substrate
n/a
IC50
6580±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93722
Synonyms:
(E)-3-(3-chloro-4-fluoro-anilino)-1-(2-furyl)prop-2-en-1-one | (E)-3-(3-chloro-4-fluoroanilino)-1-(2-furanyl)-2-propen-1-one | (E)-3-(3-chloro-4-fluoroanilino)-1-(furan-2-yl)prop-2-en-1-one | (E)-3-[(3-chloranyl-4-fluoranyl-phenyl)amino]-1-(furan-2-yl)prop-2-en-1-one | 3-[(3-chloro-4-fluorophenyl)amino]-1-(2-furyl)-2-propen-1-one | MLS000049015 | SMR000074262 | cid_2196534
Type:
Small organic molecule
Emp. Form.:
C13H9ClFNO2
Mol. Mass.:
265.667
SMILES:
Fc1ccc(cc1Cl)N=CCC(=O)c1ccco1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: