Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM58634
Substrate
n/a
EC50
1307±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM58634
Synonyms:
MLS001083165 | N-ethyl-2-(3-keto-1-phenethyl-piperazin-2-yl)-N-(2-pyrazol-1-ylethyl)acetamide | N-ethyl-2-[3-oxidanylidene-1-(2-phenylethyl)piperazin-2-yl]-N-(2-pyrazol-1-ylethyl)ethanamide | N-ethyl-2-[3-oxo-1-(2-phenylethyl)-2-piperazinyl]-N-[2-(1-pyrazolyl)ethyl]acetamide | N-ethyl-2-[3-oxo-1-(2-phenylethyl)piperazin-2-yl]-N-(2-pyrazol-1-ylethyl)acetamide | SMR000670317 | cid_24794239
Type:
Small organic molecule
Emp. Form.:
C21H29N5O2
Mol. Mass.:
383.4873
SMILES:
CCN(CCn1cccn1)C(=O)CC1N(CCc2ccccc2)CCNC1=O
Structure:
Search PDB for entries with ligand similarity: