Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96811
Substrate
n/a
EC50
857.57±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96811
Synonyms:
5-(3,4-dihydro-1H-isoquinolin-2-ylcarbonyl)-N-(1,3-thiazol-2-yl)-1H-imidazole-4-carboxamide | 5-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-N-(1,3-thiazol-2-yl)-1H-imidazole-4-carboxamide | 5-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-N-thiazol-2-yl-1H-imidazole-4-carboxamide | 5-[3,4-dihydro-1H-isoquinolin-2-yl(oxo)methyl]-N-(2-thiazolyl)-1H-imidazole-4-carboxamide | MLS002206728 | SMR001306558 | cid_42601283
Type:
Small organic molecule
Emp. Form.:
C17H15N5O2S
Mol. Mass.:
353.398
SMILES:
O=C(Nc1nccs1)c1nc[nH]c1C(=O)N1CCc2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: