Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97170
Substrate
n/a
IC50
362.58±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97170
Synonyms:
2-[6-(benzylamino)purin-9-yl]-1-[4-(2,4,6-trimethylbenzyl)piperazino]ethanone | 2-[6-(benzylamino)purin-9-yl]-1-[4-[(2,4,6-trimethylphenyl)methyl]piperazin-1-yl]ethanone | 2-[6-[(phenylmethyl)amino]-9-purinyl]-1-[4-[(2,4,6-trimethylphenyl)methyl]-1-piperazinyl]ethanone | 2-[6-[(phenylmethyl)amino]purin-9-yl]-1-[4-[(2,4,6-trimethylphenyl)methyl]piperazin-1-yl]ethanone | MLS002632722 | SMR001544327 | cid_44601539
Type:
Small organic molecule
Emp. Form.:
C28H33N7O
Mol. Mass.:
483.6079
SMILES:
Cc1cc(C)c(CN2CCN(CC2)C(=O)Cn2cnc3c(NCc4ccccc4)ncnc23)c(C)c1
Structure:
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