Reaction Details Report a problem with these data
Target
Protein kinase C alpha type
Ligand
BDBM98664
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
30±0.0 nM
Citation
 Wender, PA Bryostatin analogues, synthetic methods and uses US Patent  US8497385 Publication Date 7/30/2013 
Target
Name:
Protein kinase C alpha type
Synonyms:
KPCA_RAT | Pkca | Prkca | Protein kinase C (PKC) | Protein kinase C alpha | Protein kinase C alpha type
Type:
Protein
Mol. Mass.:
76797.67
Organism:
Rattus norvegicus (Rat)
Description:
P05696
Residue:
672
Sequence:
MADVYPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV
  
Inhibitor
Name:
BDBM98664
Synonyms:
US8497385, 19B.4
Type:
Small organic molecule
Emp. Form.:
C55H86O13
Mol. Mass.:
955.2635
SMILES:
CCCCCCCCCCCC\C=C\c1ccc(cc1)[C@@H]1C[C@@H]2CCO[C@@H](O2)\C=C\C(C)(C)[C@]2(O)O[C@@H](C\C(=C/C(=O)OC)[C@@H]2OC(=O)CCCCCCC)C[C@H](CO)OC(=O)C[C@H](O)CCO1 |r,t:30|
Structure:
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