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Target
Mu-type opioid receptor
Ligand
BDBM114603
Substrate
n/a
Meas. Tech.
Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
92470±n/a nM
Citation
 PubChem, PC Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1) PubChem Bioassay (2013)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Human
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM114603
Synonyms:
N-[[3-(2-fluorophenyl)-1-methyl-4-pyrazolyl]methyl]-1-[1-(3-methoxyphenyl)-4-pyrazolyl]methanamine | N-[[3-(2-fluorophenyl)-1-methyl-pyrazol-4-yl]methyl]-1-[1-(3-methoxyphenyl)pyrazol-4-yl]methanamine | N-[[3-(2-fluorophenyl)-1-methylpyrazol-4-yl]methyl]-1-[1-(3-methoxyphenyl)pyrazol-4-yl]methanamine | SR-01000757080 | SR-01000757080-2 | [3-(2-fluorophenyl)-1-methyl-pyrazol-4-yl]methyl-[[1-(3-methoxyphenyl)pyrazol-4-yl]methyl]amine | cid_16189988
Type:
Small organic molecule
Emp. Form.:
C22H22FN5O
Mol. Mass.:
391.4414
SMILES:
COc1cccc(c1)-n1cc(CNCc2cn(C)nc2-c2ccccc2F)cn1
Structure:
Search PDB for entries with ligand similarity: