Reaction Details Report a problem with these data
Target
Galectin-1
Ligand
BDBM120772
Substrate
n/a
Meas. Tech.
Fluorescence Polarization-Based Assay
Kd
1500±n/a nM
Citation
 Leffler, H; Nilsson, UJ; Von Wachenfeldt, H Galactoside inhibitors of galectins US Patent  US8703720 Publication Date 4/22/2014 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM120772
Synonyms:
US8703720, 16
Type:
Small organic molecule
Emp. Form.:
C28H30F2N6O5S
Mol. Mass.:
600.637
SMILES:
OCC1O[C@@H](S[C@@H]2CCCC(C2O)n2cc(nn2)-c2cccc(F)c2)C(O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1 |r|
Structure:
Search PDB for entries with ligand similarity: