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Target
Peroxisome proliferator-activated receptor gamma [205-505]
Ligand
BDBM190470
Substrate
n/a
Meas. Tech.
Reporter Gene Assay
EC50
2500±n/a nM
Citation
 Broo, A; Gottfries, J; Kossenjans, M; Lanna, L; Lindstedt-Alstermark, E; Nilsson, KA; Ohlsson, B; Thorstensson, M; Boije, M 2-substituted-3-phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease US Patent  US9181181 Publication Date 11/10/2015 
Target
Name:
Peroxisome proliferator-activated receptor gamma [205-505]
Synonyms:
NR1C3 | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor gamma (PPAR gamma)
Type:
Enzyme
Mol. Mass.:
34359.99
Organism:
Homo sapiens (Human)
Description:
P37231: amino acid 205-505
Residue:
301
Sequence:
HNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM190470
Synonyms:
US9181181, 8
Type:
Small organic molecule
Emp. Form.:
C27H27FO5S
Mol. Mass.:
482.564
SMILES:
COc1ccc(CC(=O)OCc2ccc(CC(SCCc3ccc(F)cc3)C(O)=O)cc2)cc1
Structure:
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