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Target
Oxidized low-density lipoprotein receptor 1
Ligand
BDBM454338
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
>300000±n/a nM
Citation
 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof US Patent  US10717734 Publication Date 7/21/2020 
Target
Name:
Oxidized low-density lipoprotein receptor 1
Synonyms:
LOX-1 | LOX1 | Lectin-like oxLDL receptor 1 | Lectin-like oxidized LDL receptor 1 | Lectin-type oxidized LDL receptor 1 | OLR1 | OLR1_BOVIN | Ox-LDL receptor 1 | bLOX-1
Type:
Protein
Mol. Mass.:
30894.65
Organism:
Bovine
Description:
P79391
Residue:
270
Sequence:
MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ
  
Inhibitor
Name:
BDBM454338
Synonyms:
US10717734, Compound 14
Type:
Small organic molecule
Emp. Form.:
C20H23FN4O2S
Mol. Mass.:
402.486
SMILES:
Cc1c(Cc2ccc(cn2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN
Structure:
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