Reaction Details
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Target
Galectin-1
Ligand
BDBM508748
Substrate
n/a
Meas. Tech.
fluorescence anisotropy assay
Kd
82.0±n/a nM
Citation
More Info.:
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Human
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
Inhibitor
Name:
BDBM508748
Synonyms:
3-Chloro-4-methylphenyl 3-deoxy-3-[4-(2-hydroxythiazol-4-yl)-1H-1,2,3-triazol-1-yl]-1-thio-α-D-galactopyranoside | US11046725, Example 26
Type:
Small organic molecule
Emp. Form.:
C18H19ClN4O5S2
Mol. Mass.:
470.95
SMILES:
Cc1ccc(S[C@H]2OC(CO)[C@H](O)[C@@H](C2O)n2cc(nn2)-c2csc(O)n2)cc1Cl |r|