Reaction Details Report a problem with these data
Target
Small ubiquitin-related modifier 1
Ligand
BDBM621210
Substrate
n/a
Meas. Tech.
SAE High Throughput Biochemical Assay Protocol
IC50
900±n/a nM
Citation
 Ouyang, X; Kubota, MD; Tasker, AS; Hong, F; Walton, M; Cee, VJ 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF US Patent  US20230303584 Publication Date 9/28/2023 
Target
Name:
Small ubiquitin-related modifier 1
Synonyms:
SMT3C | SMT3H3 | SUMO1 | SUMO1_HUMAN | Small ubiquitin-related modifier 1 | UBL1
Type:
Protein
Mol. Mass.:
11553.84
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
101
Sequence:
MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV
  
Inhibitor
Name:
BDBM621210
Synonyms:
US20230303584, Compound 304
Type:
Small organic molecule
Emp. Form.:
C24H22ClF3N4O2S
Mol. Mass.:
522.97
SMILES:
CC(=O)NCCn1cc(c(n1)C(F)(F)F)-c1ccccc1[C@@H]1CN(Cc2sc(Cl)cc12)C(=O)C=C
Structure:
Search PDB for entries with ligand similarity: