Reaction Details Report a problem with these data
Target
Small ubiquitin-related modifier 1
Ligand
BDBM621233
Substrate
n/a
Meas. Tech.
SAE High Throughput Biochemical Assay Protocol
IC50
940±n/a nM
Citation
 Ouyang, X; Kubota, MD; Tasker, AS; Hong, F; Walton, M; Cee, VJ 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF US Patent  US20230303584 Publication Date 9/28/2023 
Target
Name:
Small ubiquitin-related modifier 1
Synonyms:
SMT3C | SMT3H3 | SUMO1 | SUMO1_HUMAN | Small ubiquitin-related modifier 1 | UBL1
Type:
Protein
Mol. Mass.:
11553.84
Organism:
Human
Description:
n/a
Residue:
101
Sequence:
MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV
  
Inhibitor
Name:
BDBM621233
Synonyms:
US20230303584, Compound 335
Type:
Small organic molecule
Emp. Form.:
C24H24ClF3N4OS
Mol. Mass.:
508.987
SMILES:
CN(C)C\C=C\C(=O)N1C[C@H](c2cc(Cl)sc2C1)c1ccccc1-c1cn(C)nc1C(F)(F)F
Structure:
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