Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM393650
Substrate
n/a
Meas. Tech.
Activity Assay
EC50
>300±n/a nM
Citation
 Yang, J; Kim, JW; Lee, HK; Kim, JH; Son, CM; Lee, null; Choi, H; Kim, null; Ha, T; Rhee, J 3-(4-(benzyloxy)phenyl)hex-4-ynoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient US Patent  US9969723 Publication Date 5/15/2018 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM393650
Synonyms:
US9969723, 32
Type:
Small organic molecule
Emp. Form.:
C32H33NO5S
Mol. Mass.:
543.673
SMILES:
CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC(=CC3)c3ccc(cc3)S(C)(=O)=O)cc2)cc1 |c:22|
Structure:
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