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Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM400840
Substrate
n/a
Meas. Tech.
Enzyme Assay
IC50
>1000±n/a nM
Citation
 Li, Y; Burns, DM; Feng, H; Huang, T; Mei, S; Pan, J; Ye, H; Zhu, W; Rafalski, M; Wang, A; Xue, C Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors US Patent  US10000507 Publication Date 6/19/2018 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Homo sapiens (Human)
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM400840
Synonyms:
2-Amino-N-[5-(1,4-diazepan-1-yl)-1-methyl-1H-pyrazol-4-yl]thieno[3,2-b]pyridine-3-carboxamide | US10000507, Example 4
Type:
Small organic molecule
Emp. Form.:
C17H21N7OS
Mol. Mass.:
371.46
SMILES:
Cn1ncc(NC(=O)c2c(N)sc3cccnc23)c1N1CCCNCC1
Structure:
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