Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37111
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR
EC50
36210±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37111
Synonyms:
5-[(6-bromanyl-1,3-benzodioxol-5-yl)methylsulfanyl]-1-(2-methoxyphenyl)-1,2,3,4-tetrazole | 5-[(6-bromo-1,3-benzodioxol-5-yl)methylsulfanyl]-1-(2-methoxyphenyl)tetrazole | 5-[(6-bromo-1,3-benzodioxol-5-yl)methylthio]-1-(2-methoxyphenyl)tetrazole | 5-{[(6-bromo-1,3-benzodioxol-5-yl)methyl]thio}-1-(2-methoxyphenyl)-1H-tetrazole | MLS000051400 | SMR000079575 | cid_1253064
Type:
Small organic molecule
Emp. Form.:
C16H13BrN4O3S
Mol. Mass.:
421.268
SMILES:
COc1ccccc1-n1nnnc1SCc1cc2OCOc2cc1Br
Structure:
Search PDB for entries with ligand similarity: