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Target
Mevalonate kinase
Ligand
BDBM38177
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38177
Synonyms:
2-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-furamide | 2-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-furancarboxamide | 2-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]furan-3-carboxamide | MLS000065597 | SMR000080230 | cid_1244222
Type:
Small organic molecule
Emp. Form.:
C9H6F3N3O2S
Mol. Mass.:
277.223
SMILES:
Cc1occc1C(=O)Nc1nnc(s1)C(F)(F)F
Structure:
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