Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM36845
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
IC50
9050±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM36845
Synonyms:
5-tert-Butyl-2-methyl-2H-pyrazole-3-carboxylic acid 4-(2-oxo-pyrrolidin-1-yl)-benzylamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]methyl]pyrazole-3-carboxamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxo-1-pyrrolidinyl)phenyl]methyl]-3-pyrazolecarboxamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]pyrazole-3-carboxamide | 5-tert-butyl-N-[4-(2-ketopyrrolidino)benzyl]-2-methyl-pyrazole-3-carboxamide | MLS000074502 | SMR000007305 | cid_648690
Type:
Small organic molecule
Emp. Form.:
C20H26N4O2
Mol. Mass.:
354.446
SMILES:
Cn1nc(cc1C(=O)NCc1ccc(cc1)N1CCCC1=O)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: