Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM42384
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
25.42±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM42384
Synonyms:
2-(2-phenylethylsulfanyl)pyridine-3-carboxylic acid | 2-(2-phenylethylthio)-3-pyridinecarboxylic acid | 2-(phenethylthio)nicotinic acid | 2-[(2-phenylethyl)thio]nicotinic acid | MLS000088004 | SMR000072200 | cid_888706
Type:
Small organic molecule
Emp. Form.:
C14H13NO2S
Mol. Mass.:
259.324
SMILES:
OC(=O)c1cccnc1SCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: