Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43661
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43661
Synonyms:
4-Methyl-thiazole-5-carboxylic acid (4,5,6,7-tetrahydro-benzothiazol-2-yl)-amide | 4-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-1,3-thiazole-5-carboxamide | 4-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-5-thiazolecarboxamide | 4-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)thiazole-5-carboxamide | MLS000074500 | SMR000007300 | cid_653744
Type:
Small organic molecule
Emp. Form.:
C12H13N3OS2
Mol. Mass.:
279.381
SMILES:
Cc1ncsc1C(=O)Nc1nc2CCCCc2s1
Structure:
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