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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46262
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
>100000±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46262
Synonyms:
4-chloranyl-3-sulfamoyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide | 4-chloro-3-sulfamoyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide | 4-chloro-3-sulfamoyl-N-tetralin-1-yl-benzamide | MLS-0412137.0001 | cid_25048313
Type:
Small organic molecule
Emp. Form.:
C17H17ClN2O3S
Mol. Mass.:
364.846
SMILES:
NS(=O)(=O)c1cc(ccc1Cl)C(=O)NC1CCCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: