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Target
Bcl-2-like protein 2
Ligand
BDBM32268
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
3680±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32268
Synonyms:
6,7-dimethoxy-4-(3-methoxypropylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-[(3-methoxypropyl)amino]quinazoline-2(1H)-thione | MLS000045003 | SMR000026607 | cid_3239921
Type:
Small organic molecule
Emp. Form.:
C14H19N3O3S
Mol. Mass.:
309.384
SMILES:
COCCCNc1[nH]c(=S)nc2cc(OC)c(OC)cc12
Structure:
Search PDB for entries with ligand similarity: