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Target
Bcl-2-like protein 2
Ligand
BDBM32284
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
490±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Human
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32284
Synonyms:
(6E)-2-methoxy-6-[([1,2,4]triazolo[3,4-a]phthalazin-6-ylhydrazo)methylidene]-1-cyclohexa-2,4-dienone | (6E)-2-methoxy-6-[[2-([1,2,4]triazolo[3,4-a]phthalazin-6-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one | (6E)-2-methoxy-6-[[N'-([1,2,4]triazolo[3,4-a]phthalazin-6-yl)hydrazino]methylene]cyclohexa-2,4-dien-1-one | 2-Methoxy-6-([1,2,4]triazolo[3,4-a]phthalazin-6-yl-hydrazonomethyl)-phenol | MLS000551375 | SMR000145300 | cid_5514357
Type:
Small organic molecule
Emp. Form.:
C17H14N6O2
Mol. Mass.:
334.3321
SMILES:
COc1cccc(CN=Nc2nn3cnnc3c3ccccc23)c1O |w:9.9|
Structure:
Search PDB for entries with ligand similarity: