Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43504
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43504
Synonyms:
5-amino-3-(2-methylphenyl)-1,2-oxazole-4-carbonitrile | 5-amino-3-(2-methylphenyl)-4-isoxazolecarbonitrile | 5-amino-3-(2-methylphenyl)isoxazole-4-carbonitrile | 5-amino-3-(o-tolyl)isoxazole-4-carbonitrile | 5-azanyl-3-(2-methylphenyl)-1,2-oxazole-4-carbonitrile | MLS000045809 | SMR000028206 | cid_3236239
Type:
Small organic molecule
Emp. Form.:
C11H9N3O
Mol. Mass.:
199.2087
SMILES:
Cc1ccccc1-c1noc(N)c1C#N
Structure:
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