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Target
Induced myeloid leukemia cell differentiation protein Mcl-1
Ligand
BDBM34399
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors
IC50
3359.010968±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Induced myeloid leukemia cell differentiation protein Mcl-1
Synonyms:
BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT
Type:
Membrane; Single-pass membrane protein
Mol. Mass.:
37332.87
Organism:
Human
Description:
Q07820
Residue:
350
Sequence:
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
  
Inhibitor
Name:
BDBM34399
Synonyms:
2,4-dimethyl-N-(4-methyl-1,3-benzothiazol-2-yl)-1,3-oxazole-5-carboxamide | 2,4-dimethyl-N-(4-methyl-1,3-benzothiazol-2-yl)-5-oxazolecarboxamide | 2,4-dimethyl-N-(4-methyl-1,3-benzothiazol-2-yl)oxazole-5-carboxamide | MLS000092895 | SMR000028532 | cid_3244965
Type:
Small organic molecule
Emp. Form.:
C14H13N3O2S
Mol. Mass.:
287.337
SMILES:
Cc1nc(C)c(o1)C(=O)Nc1nc2c(C)cccc2s1
Structure:
Search PDB for entries with ligand similarity: