Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM51075
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
42371±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM51075
Synonyms:
2-[[[(Z)-[2-keto-4-(3-methylpyridin-1-ium-1-yl)-3-thiazolin-5-ylidene]methyl]amino]carbamoyl]phenolate | 2-[[[(Z)-[4-(3-methyl-1-pyridin-1-iumyl)-2-oxo-5-thiazolylidene]methyl]hydrazo]-oxomethyl]phenolate | 2-[[[(Z)-[4-(3-methylpyridin-1-ium-1-yl)-2-oxidanylidene-1,3-thiazol-5-ylidene]methyl]amino]carbamoyl]phenolate | 2-[[[(Z)-[4-(3-methylpyridin-1-ium-1-yl)-2-oxo-1,3-thiazol-5-ylidene]methyl]amino]carbamoyl]phenolate | MLS000589575 | SMR000212994 | cid_15944865
Type:
Small organic molecule
Emp. Form.:
C17H14N4O3S
Mol. Mass.:
354.383
SMILES:
Cc1ccc[n+](c1)-c1[nH]c(=O)sc1C=NNC(=O)c1ccccc1[O-] |w:14.16|
Structure:
Search PDB for entries with ligand similarity: